Article
Genotype markers and proto-oncogene analysis in the CD30-positive "malignant histiocytosis" DEL cell line with t(5;6)(q35;p21).
International journal of cancer - 15 Jul 1990
Gogusev J, Barbey S, Nezelof C
Abstract excerpt
The DEL cell line isolated from a patient who died of malignant histiocytosis exhibits a reciprocal chromosomal translocation t(5;6)(5q35;6p21). The cells were analyzed for Ig(Jh), TCR beta-gene rearrangements and proto-oncogene expression pattern, using a panel of molecularly cloned probes that included c-fms, c-myc, c-myb, c-pim, c-fos, N-myc, c-sis, c-fgr as well as the virally derived probes v-ki-ras and...
Topics
- Antigens, CD
- Antigens, Differentiation
- Antigens, Neoplasm
- Blotting, Northern
- Blotting, Southern
- Cell Line
- Chromosomes, Human, Pair 5
- DNA Probes
- Gene Rearrangement, beta-Chain T-Cell Antigen Receptor
- Genetic Markers