Discover Community Create You

Loading publication...

Noodle always counts identifier-free feature events for service operation. With your permission, Google Analytics can also estimate audience and engagement. Search text, publication identifiers, cookies, IP addresses and browser fingerprints are never included in Noodle's first-party event counters.

Privacy details

Article

Oncogenic mechanisms in myeloproliferative disorders.

Cellular and molecular life sciences : CMLS - 1 Dec 2006

Delhommeau F, Pisani D F, James C, Casadevall N, Constantinescu S, Vainchenker W

Abstract excerpt

Myeloproliferative disorders (MPDs) are clonal haematopoietic malignancies involving the abnormal proliferation of myeloid lineages. The World Health Organisation (WHO) classification of haematopoietic malignancies distinguishes MPDs from myelodysplastic/ myeloproliferative disorders and systemic mastocytosis. These malignancies frequently involve constitutive tyrosine kinase activity, resulting from either...

Read the complete abstract on PubMed

Topics

Share this publication in a Topic to start or enrich a Post.

Share to Genes, abl
Share to Janus Kinase 2
Share to Mastocytosis

Methodology Data sources Editorial policy Privacy Delete account & data About Contact Helena Bioinformatics

Share to mRNA Cleavage and Polyadenylation Factors

Share to Myeloproliferative Disorders

Share to Rare Diseases

Share to Receptor, Fibroblast Growth Factor, Type 1

Share to Receptor, Platelet-Derived Growth Factor beta

Source

Open in PubMed Open full text

Identifiers

PMID: 17131059
DOI: 10.1007/s00018-006-6272-7
PMCID: PMC11136318

Genes

JAK2

Variants

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

Related research

Semantic proximity does not establish scientific evidence. Graph snapshot: 2026-09-29.

Research trail→

Click a neighbor to travelStep 1 · 12 closest

Oncogenic mechanisms in myeloproliferative disorders.PMID 17131059Read ↗

Molecular and genetic bases of myeloproliferative disorders: questions and perspectives.Semantic proximity Read ↗

A Broad Overview of Signaling in Ph-Negative Classic Myeloproliferative NeoplasmsSemantic proximity Read ↗

Myeloproliferative disordersSemantic proximity Read ↗

Aberrant signal transduction pathways in myeloproliferative neoplasms.Semantic proximity Read ↗

Molecular pathogenesis of the myeloproliferative neoplasms.Semantic proximity Read ↗

Myeloproliferative neoplasms: molecular pathophysiology, essential clinical understanding, and treatment strategies.Semantic proximity Read ↗

Oncogenes in myeloproliferative disorders.Semantic proximity Read ↗

Genetic basis of MPN: Beyond JAK2-V617F.Semantic proximity Read ↗

Myeloproliferative neoplasms: updates on molecular pathophysiology, diagnosis and treatment strategies.Semantic proximity Read ↗

[Molecular mechanisms in myeloproliferative diseases and myelodysplastic syndromes].Semantic proximity Read ↗

Biology and Current Treatment of Myeloproliferative Neoplasms.Semantic proximity Read ↗

Myeloproliferative neoplasms: contemporary diagnosis using histology and genetics.Semantic proximity Read ↗

⌁Select a neighboring publication to make it the new centre.