Oncogenes in myeloproliferative disorders.

doi:10.4161/cc.6.5.3919

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Article

Oncogenes in myeloproliferative disorders.

Cell cycle (Georgetown, Tex.) - 1 Mar 2007

Tefferi Ayalew, Gilliland D Gary

Abstract excerpt

Myeloproliferative disorders (MPDs) constitute a group of hematopoietic malignancies that feature enhanced proliferation and survival of one or more myeloid lineage cells. William Dameshek is credited for introducing the term "MPDs" in 1951 when he used it to group chronic myeloid leukemia (CML), polycythemia vera (PV), essential thrombocythemia (ET) and primary myelofibrosis (PMF) under one clinicopathologic...

Topics

Animals
Humans
Mutation
Myeloproliferative Disorders
Oncogenes
Signal Transduction

Source

Open in PubMed

Identifiers

PMID: 17351342
DOI: 10.4161/cc.6.5.3919

Genes

CEL
BCR
FGFR1
JAK2
PDGFRA
PDGFRB
PTPN11

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