Article
A T-cell neoplasia showing clinicopathologic features of malignant histiocytosis with novel chromosomal abnormalities and N-ras mutation.
Cancer - 15 Apr 1991
Itoyama T, Sadamori N, Sasagawa I, Nakamura H, Tokunaga S, Yamada Y, Ichimaru M, Yoshida T, Kikuchi M, Takeshima F
Abstract excerpt
Malignant histiocytosis (MH) is a distinct disease entity defined clinically and morphologically. However, the neoplastic origin of MH is not well established. The authors report a 26-year-old woman who showed the typical clinicopathologic features of so-called MH. Cytogenetic and molecular genetic examinations were performed in addition to the morphologic and immunologic approach. The expression of CD2 and...
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