Loading publication...

Noodle always counts identifier-free feature events for service operation. With your permission, Google Analytics can also estimate audience and engagement. Search text, publication identifiers, cookies, IP addresses and browser fingerprints are never included in Noodle's first-party event counters.

Privacy details

Article

FGFR1 is fused to the centrosome-associated proteinCEP110 in the 8p12 stem cell myeloproliferative disorder with t(8;9)(p12;q33)

1 Mar 2000

Abstract excerpt

The hallmark of the 8p12 stem cell myeloproliferative disorder (MPD) is the disruption of the FGFR1 gene, which encodes a tyrosine kinase receptor for members of the fibroblast growth factor family. FGFR1 can be fused to at least 3 partner genes at chromosomal regions 6q27, 9q33, or 13q12. We report here the cloning of the t(8;9)(p12;q33) and the detection of a novel fusion betweenFGFR1 and the CEP110 gene, which...

Source

Identifiers

PMID: 10688839
DOI: 10.1182/blood.v95.5.1788.005k15_1788_1796

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 30 Aug 2026.

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Community interpretation

Discuss the evidence

Ask a question, add context or challenge an interpretation. Community activity is separate from scientific evidence strength.

0

discussions

0

replies

Citations encouraged

Claims remain attributable.

No discussion yet

Be the first to add a careful, cited interpretation.

Related research

Semantic proximity does not establish scientific evidence.

Research trail→

Click a neighbor to travelStep 1 · 12 closest

FGFR1 is fused to the centrosome-associated proteinCEP110 in the 8p12 stem cell myeloproliferative disorder with t(8;9)(p12;q33)PMID 10688839Read ↗

The 8p11 Myeloproliferative Syndrome: A Distinct Clinical Entity Caused by Constitutive Activation of <i>FGFR1</i>Semantic proximity Read ↗

The 8p11 myeloproliferative syndrome: Genotypic and phenotypic classification and targeted therapySemantic proximity Read ↗

The t(6;8)(q27;p11) Translocation in a Stem Cell Myeloproliferative Disorder Fuses a Novel Gene, FOP, to Fibroblast Growth Factor Receptor 1Semantic proximity Read ↗

8p11 myeloproliferative syndrome with a novel t(7;8) translocation leading to fusion of the FGFR1 and TIF1 genes.Semantic proximity Read ↗

Identification of a novel partner gene, <i>TPR</i>, fused to <i>FGFR1</i> in 8p11 myeloproliferative syndromeSemantic proximity Read ↗

Fibroblast growth factor receptor 1 is fused to FIM in stem-cell myeloproliferative disorder with t(8;13)(p12;q12)Semantic proximity Read ↗

Fusion of the <i>BCR</i> and the fibroblast growth factor receptor‐1 (<i>FGFR1</i>) genes as a result of t(8;22)(p11;q11) in a myeloproliferative disorder: The first fusion gene involving <i>BCR</i> but not <i>ABL</i>Semantic proximity Read ↗

[Characteristic of 8p11 Myeloproliferative Syndrome with Rare Phenotype].Semantic proximity Read ↗

Myeloproliferative disorder FOP-FGFR1 fusion kinase recruits phosphoinositide-3 kinase and phospholipase Cgamma at the centrosome.Semantic proximity Read ↗

Identification of four new translocations involving FGFR1 in myeloid disordersSemantic proximity Read ↗

The t(1;9)(p34;q34) and t(8;12)(p11;q15) fuse pre‐mRNA processing proteins <i>SFPQ (PSF)</i> and <i>CPSF6</i> to <i>ABL</i> and <i>FGFR1</i>Semantic proximity Read ↗

Distinct stem cell myeloproliferative/T lymphoma syndromes induced by ZNF198-FGFR1 and BCR-FGFR1 fusion genes from 8p11 translocationsSemantic proximity Read ↗

⌁Select a neighboring publication to make it the new centre.