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Article

The effect of anions on the human P2X7 receptor.

Biochimica et biophysica acta - 1 Dec 2011

Kubick Christoph, Schmalzing Günther, Markwardt Fritz

Abstract excerpt

P2X7 receptors (P2X7Rs) are nonselective cation channels that are opened by the binding of extracellular ATP and are involved in the modulation of epithelial secretion, inflammation and nociception. Here, we investigated the effect of extracellular anions on channel gating and permeation of human P2X7Rs (hP2X7Rs) expressed in Xenopus laevis oocytes. Two-microelectrode voltage-clamp recordings showed that...

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Identifiers

PMID: 21872569
DOI: 10.1016/j.bbamem.2011.08.017

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 5 Sept 2026. Manifest publication-graph-cohort-2026-09-05.1.

Source receipt: pubmed, retrieved 5 Sept 2026.

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