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Article

miR-181b is a biomarker of disease progression in chronic lymphocytic leukemia

3 Jun 2011

Abstract excerpt

MicroRNAs play a crucial role in chronic lymphocytic leukemia. We investigated whether microRNAs can discriminate patients with a progressive disease from patients with a stable disease. We analyzed microRNA expression on leukemic cells isolated from 358 sequential samples of 114 patients with either stable or progressive disease. We found that during the course of the disease the expression values of miR-181b,...

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PMID: 21636858
DOI: 10.1182/blood-2011-01-333484

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