Discover Community Create You

Loading publication...

Noodle always counts identifier-free feature events for service operation. With your permission, Google Analytics can also estimate audience and engagement. Search text, publication identifiers, cookies, IP addresses and browser fingerprints are never included in Noodle's first-party event counters.

Privacy details

Article

Protein profiles distinguish stable and progressive chronic lymphocytic leukemia.

Leukemia & lymphoma - 1 May 2016

Huang Pauline Y, Mactier Swetlana, Armacki Natalie, Giles Best O, Belov Larissa, Kaufman Kimberley L, Pascovici Dana, Mulligan Stephen P, Christopherson Richard I

Abstract excerpt

Patients with a stable chronic lymphocytic leukemia (CLL) double their blood lymphocyte count in >5 years, but may develop progressive disease with lymphocytes doubling in <12 months. To identify a protein signature for progressive CLL, whole cell extracts of peripheral blood mononuclear cells from patients with CLL (n=27) were screened using iTRAQ (isobaric tags for relative and absolute quantification)...

Read the complete abstract on PubMed

Topics

Share this publication in a Topic to start or enrich a Post.

Share to Chromatography, Liquid
Share to Cluster Analysis

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Share to Immunophenotyping

Share to Leukemia, Lymphocytic, Chronic, B-Cell

Share to Neoplasm Staging

Share to Proteome

Share to Proteomics

Share to Tandem Mass Spectrometry

Source

Identifiers

PMID: 26422656
DOI: 10.3109/10428194.2015.1094692

Genes

SRM

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 4 Sept 2026.

Related research

Semantic proximity does not establish scientific evidence.

Research trail→

Click a neighbor to travelStep 1 · 12 closest

Protein profiles distinguish stable and progressive chronic lymphocytic leukemia.PMID 26422656Read ↗

Proteomic profiling based classification of CLL provides prognostication for modern therapy and identifies novel therapeutic targets.Semantic proximity Read ↗

Proteomics and metabolomics identify molecular mechanisms of aging potentially predisposing for chronic lymphocytic leukemiaSemantic proximity Read ↗

Proteomics Profiling of CLL Versus Healthy B-cells Identifies Putative Therapeutic Targets and a Subtype-independent Signature of Spliceosome DysregulationSemantic proximity Read ↗

Proteogenomics refines the molecular classification of chronic lymphocytic leukemiaSemantic proximity Read ↗

Proteogenomics refines the molecular classification of chronic lymphocytic leukemia.Semantic proximity Read ↗

Total proteome analysis identifies migration defects as a major pathogenetic factor in immunoglobulin heavy chain variable region (IGHV)-unmutated chronic lymphocytic leukemia.Semantic proximity Read ↗

Cell surface phenotype profiles distinguish stable and progressive chronic lymphocytic leukemia.Semantic proximity Read ↗

The protein landscape of chronic lymphocytic leukemia.Semantic proximity Read ↗

Proteomics in Childhood Acute Lymphoblastic Leukemia: Challenges and OpportunitiesSemantic proximity Read ↗

Glycoproteome remodeling in MLL-rearranged B-cell precursor acute lymphoblastic leukemiaSemantic proximity Read ↗

Unveiling the omics tapestry of B-acute lymphoblastic leukemia: bridging genomics, metabolomics, and immunomicsSemantic proximity Read ↗

RPPA-based proteomics recognizes distinct epigenetic signatures in chronic lymphocytic leukemia with clinical consequences.Semantic proximity Read ↗

⌁Select a neighboring publication to make it the new centre.