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Article

Tcl1 Expression in Chronic Lymphocytic Leukemia Is Regulated by <i>miR-29</i> and <i>miR-181</i>

15 Dec 2006

Abstract excerpt

B-cell chronic lymphocytic leukemia (B-CLL) is the most common human leukemia in the world. Deregulation of the TCL1 oncogene is a causal event in the pathogenesis of the aggressive form of this disease as was verified by using animal models. To study the mechanism of Tcl1 regulation in CLL, we carried out microRNA expression profiling of three types of CLL: indolent CLL, aggressive CLL, and aggressive CLL...

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Identifiers

PMID: 17178851
DOI: 10.1158/0008-5472.can-06-3613

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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