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Article

Role of microRNA in chronic lymphocytic leukemia onset and progression

19 Feb 2015

Abstract excerpt

B-cell chronic lymphocytic leukemia (CLL) is the most common human leukemia occurring as indolent or aggressive form. CLL clinical features and genetic abnormalities are well documented, but molecular details are still under investigation. MicroRNAs are small non-coding RNAs involved in several cellular processes and expressed in a tissue-specific manner. MicroRNAs regulate gene expression, and their deregulation...

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PMID: 25886051
DOI: 10.1186/s13045-015-0112-x

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