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Article

High-level expression and purification of MyoD, myogenin, and E12.

Protein expression and purification - 1 Feb 1997

Maleki S J, Hurlburt B K

Abstract excerpt

The myogenic regulatory factors (MRFs), MyoD, myogenin, Myf-5, and MRF4, function as transcriptional activators of muscle-specific gene expression by forming heterodimers with the ubiquitously expressed products of the E2A gene, E12 and E47. To enable quantitative biochemical and biophysical analyses of the wild-type proteins, as well as mutants designed to reveal structure-function relationships, we developed...

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Identifiers

PMID: 9116507
DOI: 10.1006/prep.1996.0669

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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