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Article

Functional interaction between dynein light chain and intermediate chain is required for mitotic spindle positioning.

Molecular biology of the cell - 1 Aug 2011

Stuchell-Brereton Melissa D, Siglin Amanda, Li Jun, Moore Jeffrey K, Ahmed Shubbir, Williams John C, Cooper John A

Abstract excerpt

Cytoplasmic dynein is a large multisubunit complex involved in retrograde transport and the positioning of various organelles. Dynein light chain (LC) subunits are conserved across species; however, the molecular contribution of LCs to dynein function remains controversial. One model suggests that LCs act as cargo-binding scaffolds. Alternatively, LCs are proposed to stabilize the intermediate chains (ICs) of the...

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Identifiers

PMID: 21633107
DOI: 10.1091/mbc.E11-01-0075
PMCID: PMC3145545

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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