Article
Mitotic spindle positioning in Saccharomyces cerevisiae is accomplished by antagonistically acting microtubule motor proteins.
The Journal of cell biology - 8 Sept 1997
Cottingham F R, Hoyt M A
Abstract excerpt
Proper positioning of the mitotic spindle is often essential for cell division and differentiation processes. The asymmetric cell division characteristic of budding yeast, Saccharomyces cerevisiae, requires that the spindle be positioned at the mother-bud neck and oriented along the mother-bud axis. The single dynein motor encoded by the S. cerevisiae genome performs an important but nonessential...
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