Article
NAMPT -3186C/T polymorphism affects repaglinide response in Chinese patients with Type 2 diabetes mellitus.
Clinical and experimental pharmacology & physiology - 1 Aug 2011
Sheng Fei-Feng, Dai Xing-Ping, Qu Jian, Lei Guang-Hua, Lu Hong-Bin, Wu Jing, Xu Xiao-Jing, Pei Qi, Dong Min, Liu Ying-Zi, Zhou Hong-Hao, Liu Zhao-Qian
Abstract excerpt
1. In the present study, we investigated the associations of nicotinamide phosphoribosyltransferase (NAMPT)-3186 C/T and -948G/T polymorphisms with the risk of Type 2 diabetes mellitus (T2DM) and their impact on the efficacy of repaglinide in Chinese Han T2DM patients. 2. In all, 170 patients with T2DM and 129 healthy controls were genotyped for NAMPT-948G>T and -3186C>T polymorphisms. Thirty-five patients with...
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