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Article

A variant of GRK5 is associated with the therapeutic efficacy of repaglinide in Chinese Han patients with type 2 diabetes mellitus.

Drug development research - 1 May 2018

Shang Zhenhai, Han Feifei, Zhou Xueyan, Bao Zejun, Zhu Jing, Wang Tao, Lu Qian, Du Lei, Li Wei, Lv Dongmei, Yin Xiaoxing

Abstract excerpt

Post-Market Research We aimed to investigate the impact of G protein-coupled receptor kinase 5 (GRK5) rs10886471 polymorphism on repaglinide efficacy in Chinese patients with type 2 diabetes mellitus (T2DM). A total of 300 T2DM patients and 210 healthy controls were genotyped for GRK5 rs10886471 on a three-dimensional polyacrylamide gel-based DNA microarray. Eighty-five patients with the same genotypes of...

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Source

Identifiers

PMID: 29663513
DOI: 10.1002/ddr.21426

Genes

GRK5

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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