Article
Effect of genetic polymorphism of UCP2-866 G/A on repaglinide response in Chinese patients with type 2 diabetes.
Die Pharmazie - 1 Jan 2012
Wang Shan, Se Yan-Mei, Liu Zhao-Qian, Lei Ming-Xiang, Hao-BoYang, Sun Zhi-Xiang, Nie Sheng-Dan, Zeng Xiao-min, Wu Jing
Abstract excerpt
The aim of the present study was to evaluate the impact of the UCP2-866 G/A polymorphism on the efficacy of repaglinide in treating patients with diabetes mellitus type 2 (T2DM). 370 patients with T2DM and 166 healthy volunteers were enrolled to identify UCP2-866 G/A genotypes. 16 patients with GG genotype, 14 with GA genotype and 11 with AA genotype of UCP2-866 G/A underwent an 8-week repaglinide treatment...
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