Article
Evaluation of the effect of MTNR1B rs10830963 gene variant on the therapeutic efficacy of nateglinide in treating type 2 diabetes among Chinese Han patients.
BMC medical genomics - 12 Jun 2021
Song Jin-Fang, Zhang Jie, Zhang Ming-Zhu, Ni Jiang, Wang Tao, Zhao Yi-Qing, Khan Naveed Ullah
Abstract excerpt
Genetic polymorphisms in the MTNR1B gene is associated with type 2 diabetes mellitus (T2DM); however, there is no evidence about its impact on the therapeutic efficacy of nateglinide. This prospective case-control study was designed to investigate the effect of MTNR1B rs10830963 gene variant on the therapeutic efficacy of nateglinide in treating T2DM. We genotyped untreated T2DM patients (N = 200) and healthy...
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