Article
Association of KCNJ11 and ABCC8 genetic polymorphisms with response to repaglinide in Chinese diabetic patients.
Acta pharmacologica Sinica - 1 Aug 2008
He Ya-yi, Zhang Rong, Shao Xin-yu, Hu Cheng, Wang Cong-rong, Lu Jun-xi, Bao Yu-qian, Jia Wei-ping, Xiang Kun-san
Abstract excerpt
AIM: The aim of this study was to investigate the association of KCNJ11 E23K and ABCC8 exon16-3T/C with the therapeutic effect of repaglinide in patients with type 2 diabetes. METHODS: A total of 100 Chinese patients with newly diagnosed type 2 diabetes were treated with repaglinide for 24 weeks. Arginine stimulation tests were performed to evaluate beta cell function. Gene variations were detected with...
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