Article
NeuroD1 A45T and PAX4 R121W polymorphisms are associated with plasma glucose level of repaglinide monotherapy in Chinese patients with type 2 diabetes.
British journal of clinical pharmacology - 1 Sept 2012
Gong Zhi-Cheng, Huang Qiong, Dai Xing-Ping, Lei Guang-Hua, Lu Hong-Bin, Yin Ji-Ye, Xu Xiao-Jing, Qu Jian, Pei Qi, Dong Min, Zhou Bo-Ting, Shen Jie, Zhou Gan, Zhou Hong-Hao, Liu Zhao-Qian
Abstract excerpt
AIMS: We aimed to determine whether NeuroD1/BETA2 and PAX4 polymorphisms were associated with the therapeutic efficacy of repaglinide in Chinese type 2 diabetes mellitus (T2DM) patients. METHODS: Three hundred and sixty-eight T2DM patients and 132 healthy control subjects were genotyped by restriction fragment length polymorphism. Forty-three patients with various genotypes were randomly selected to undergo 8...
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