Article
T cell receptor-bearing cells among rat intestinal intraepithelial lymphocytes are mainly alpha/beta+ and are thymus dependent.
European journal of immunology - 1 May 1990
Vaage J T, Dissen E, Ager A, Roberts I, Fossum S, Rolstad B
Abstract excerpt
Rearrangement of both the beta and gamma chain T cell receptor (TcR) genes was detected in intestinal intraepithelial lymphocytes (IEL) from normal euthymic rats. Flow cytometric analyses showed that about 73% of the IEL were CD3+ (1F4) and that 67% were TcR alpha/beta+ (R73). About 5% of the IEL...
Topics
- Animals
- Gene Rearrangement, alpha-Chain T-Cell Antigen Receptor
- Gene Rearrangement, beta-Chain T-Cell Antigen Receptor
- Intestinal Mucosa
- Phenotype
- Rats
- Rats, Nude
- Receptors, Antigen, T-Cell
- Receptors, Antigen, T-Cell, alpha-beta
- T-Lymphocytes
- Thymus Gland