Article
Phenotypic and functional characterization of human TCR gamma delta+ intestinal intraepithelial lymphocytes.
Current topics in microbiology and immunology - 1 Jan 1991
Deusch K, Pfeffer K, Reich K, Gstettenbauer M, Daum S, Lüling F, Classen M
Abstract excerpt
Intestinal intraepithelial lymphocytes (IEL) appear to represent a peculiar set of immune cells compartmentalized at the interface between the organism and the external environment. In previous studies we observed that within human IEL TCR-tau/delta T cells represent a major fraction that predominantly express the CD8 molecule and preferentially uses the V-delta-1 gene segment. Thus these data suggested a...
Topics
- Adult
- Antigens, CD
- Colon
- Epithelial Cells
- Epithelium
- Humans
- Intestines
- Lymphocyte Subsets
- Phenotype
- Receptors, Antigen, T-Cell, gamma-delta
