Age-associated increase in number of CD4+CD8+ intestinal intraepithelial lymphocytes in rats.

doi:10.1002/eji.1830220124

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Article

Age-associated increase in number of CD4+CD8+ intestinal intraepithelial lymphocytes in rats.

European journal of immunology - 1 Jan 1992

Takimoto H, Nakamura T, Takeuchi M, Sumi Y, Tanaka T, Nomoto K, Yoshikai Y

Abstract excerpt

A significant number of CD4+CD8+ T cells were detected in intestinal intraepithelial lymphocytes (IEL) of various strains of rats including Wistar, WKA, BN, LEW and F344. The site of the CD4+CD8+ population in IEL increased with age in all strains we examined. Most IEL bearing CD8 expressed no CD...

Topics

Age Factors
Animals
Antigens, CD
CD4-CD8 Ratio
CD5 Antigens
Germ-Free Life
Intestinal Mucosa
Lymphocyte Activation
Phenotype
Rats
Rats, Nude
T-Lymphocytes

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