Article
Repertoire of the alpha beta T-cell receptor in the intestine.
Immunological reviews - 1 Feb 2007
Probert Christopher S J, Saubermann Lawrence J, Balk Steven, Blumberg Richard S
Abstract excerpt
The majority of T cells in the human and mouse intestine express the T-cell receptor (TCR) as an alphabeta heterodimer on their cell surface. As the major recognition element of antigens in the context of major histocompatibility complex-derived proteins, an examination of the structure of the alpha beta TCR in intestines has provided significant insights into the potential function of these cells and the major...
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