Article
Genotoxicity of m-phenylenediamine and 2-aminofluorene in Salmonella typhimurium and human lymphocytes with and without plant activation.
Environmental and molecular mutagenesis - 1 Jan 1995
Plewa M J, Wagner E D, Yu T W, Anderson D
Abstract excerpt
The promutagenic arylamines, m-phenylenediamine (mPDA) and 2-aminofluorene (2-AF), were evaluated for their genotoxicity in Salmonella typhimurium strain YG1024 and in human lymphocytes. These agents were assayed with and without TX1MX plant activation mix. Both arylamines without activation were...
Topics
- Adult
- Cell Survival
- DNA Damage
- Female
- Fluorenes
- Humans
- Lymphocytes
- Mutagenicity Tests
- Mutagens
- Mutation
- Phenylenediamines
- Plant Extracts
- Plants, Toxic
- Salmonella typhimurium
- Nicotiana