A C to T polymorphism of urokinase plasminogen activator (P141L) is associated with Helicobacter pylori infection.

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Article

A C to T polymorphism of urokinase plasminogen activator (P141L) is associated with Helicobacter pylori infection.

Asian Pacific journal of cancer prevention : APJCP - 1 Jan 2011

Goto Yasuyuki, Hagikura Shoichi, Katsuda Nobuyuki, Hamajima Nobuyuki

Abstract excerpt

Urokinase plasminogen activator (uPA) plays an important role in tumor invasion and certain inflammatory diseases. However, few studies have paid attention to how the uPA is associated with Helicobacter pylori infection and gastric atrophy. This study investigated associations of a C-to-T polymorphism of uPA (P141L, rs2227564) in exon 6 in 454 Japanese health checkup examinees (126 males and 328 females) aged 35...

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PMID: 21627387

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