Association between promoter region of the uPAR (rs344781) gene polymorphism in genetic susceptibility to migraine without aura in three Iranian hospitals.

doi:10.1016/j.clineuro.2014.02.003

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Article

Association between promoter region of the uPAR (rs344781) gene polymorphism in genetic susceptibility to migraine without aura in three Iranian hospitals.

Clinical neurology and neurosurgery - 1 May 2014

Zandifar Alireza, Soleimani Samira, Iraji Niloufar, Haghdoost Faraidoon, Tajaddini Mohamadhasan, Javanmard Shaghayegh Haghjooy

Abstract excerpt

INTRODUCTION: Migraine is a chronic neurological disorder. Inflammation has a key role in migraine pathophysiology. Urokinase plasminogen activator receptor (uPAR) directly involves in inflammatory conditions by facilitating migration of inflammatory cells to different tissues. The aim of this study was to investigate whether uPAR rs344781, common genetic polymorphism in the uPAR promoter region, might be...

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PMID: 24731575
DOI: 10.1016/j.clineuro.2014.02.003

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