Article
Genetic polymorphism of urokinase-type plasminogen activator is interacting with plasminogen activator inhibitor-1 to raise risk of cervical neoplasia.
Journal of surgical oncology - 1 Aug 2012
Tee Yi-Torng, Wang Po-Hui, Tsai Hsiu-Ting, Lin Long-Yau, Lin Hung-Ting, Yang Shun-Fa, Hsieh Yi-Hsien, Ying Tsung-Ho
Abstract excerpt
BACKGROUND AND OBJECTIVES: To evaluate the impact of plasminogen activator (PA) system genes, including urokinase plasminogen activator (uPA), uPA receptor (uPAR), and plasminogen activator inhibitor-1 (PAI-1) gene polymorphisms in patients with the cervical neoplasia. METHODS: In total, 336 blood samples were collected from healthy women and 136 patients with cervical neoplasia to analyze the gene polymorphisms...
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