Article
The association of miR-146a rs2910164 and miR-196a2 rs11614913 polymorphisms with cancer risk: a meta-analysis of 32 studies.
Mutagenesis - 1 Nov 2012
Wang Jianbo, Wang Qingwei, Liu Hong, Shao Na, Tan Bingxu, Zhang Guangyu, Wang Kai, Jia Yibin, Ma Wei, Wang Nana, Cheng Yufeng
Abstract excerpt
MicroRNAs (miRNAs) are small non-coding RNA molecules, which act as post-transcriptional regulators of gene expression and have been implicated in initiation, progression and treatment outcome of diverse cancers. Single nucleotide polymorphisms (SNPs), as the most common type of genetic variation, also exist in miRNA genes and can lead to alteration in miRNA expression resulting in diverse functional...
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