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Article

Comprehensive review of genetic association studies and meta-analyses on miRNA polymorphisms and cancer risk.

PloS one - 1 Jan 2012

Srivastava Kshitij, Srivastava Anvesha

Abstract excerpt

BACKGROUND: MicroRNAs (miRNAs) are small RNA molecules that regulate the expression of corresponding messenger RNAs (mRNAs). Variations in the level of expression of distinct miRNAs have been observed in the genesis, progression and prognosis of multiple human malignancies. The present study was aimed to investigate the association between four highly studied miRNA polymorphisms (mir-146a rs2910164, mir-196a2...

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Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

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Identifiers

PMID: 23226435
DOI: 10.1371/journal.pone.0050966
PMCID: PMC3511416

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