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Article

Stepwise Differentiation of Mesenchymal Stem Cells Augments Tendon-Like Tissue Formation and Defect Repair In Vivo.

Stem cells translational medicine - 1 Aug 2016

Yin Zi, Guo Jia, Wu Tian-Yi, Chen Xiao, Xu Liang-Liang, Lin Si-En, Sun Yun-Xin, Chan Kai-Ming, Ouyang Hongwei, Li Gang

Abstract excerpt

UNLABELLED: : Tendon injuries are common and present a clinical challenge, as they often respond poorly to treatment and result in long-term functional impairment. Inferior tendon healing responses are mainly attributed to insufficient or failed tenogenesis. The main objective of this study was to establish an efficient approach to induce tenogenesis of bone marrow-derived mesenchymal stem cells (BMSCs), which...

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Identifiers

PMID: 27280798
DOI: 10.5966/sctm.2015-0215
PMCID: PMC4954446

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