Discover Community Create You

Loading publication...

Noodle always counts identifier-free feature events for service operation. With your permission, Google Analytics can also estimate audience and engagement. Search text, publication identifiers, cookies, IP addresses and browser fingerprints are never included in Noodle's first-party event counters.

Privacy details

Article

Scleraxis -Overexpressed Human Embryonic Stem Cell–Derived Mesenchymal Stem Cells for Tendon Tissue Engineering with Knitted Silk-Collagen Scaffold

13 Dec 2013

Abstract excerpt

AIM: Despite our previous study that demonstrates that human embryonic stem cells (hESCs) can be used as seed cells for tendon tissue engineering after stepwise induction, suboptimal tendon regeneration implies that a new strategy needs to be developed for tendon repair. We investigated whether overexpression of the tendon-specific transcription factor scleraxis (SCX) in hESC-derived mesenchymal stem cells...

Read the complete abstract on PubMed

Topics

Share this publication in a Topic to start or enrich a Post.

Share to Nerve injury and regeneration
Share to Tendon Structure and Treatment

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Source

Identifiers

PMID: 24328506
DOI: 10.1089/ten.tea.2012.0656

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 3 Sept 2026.

Related research

Semantic proximity does not establish scientific evidence.

Research trail→

Click a neighbor to travelStep 1 · 12 closest

Scleraxis -Overexpressed Human Embryonic Stem Cell–Derived Mesenchymal Stem Cells for Tendon Tissue Engineering with Knitted Silk-Collagen ScaffoldPMID 24328506Read ↗

Force and scleraxis synergistically promote the commitment of human ES cells derived MSCs to tenocytesSemantic proximity Read ↗

Induced pluripotent stem cell-derived tenocyte-like cells promote the regeneration of injured tendons in miceSemantic proximity Read ↗

In Vitro Comparison of 2D-Cell Culture and 3D-Cell Sheets of Scleraxis-Programmed Bone Marrow Derived Mesenchymal Stem Cells to Primary Tendon Stem/Progenitor Cells for Tendon RepairSemantic proximity Read ↗

Conversion of Human Bone Marrow-Derived Mesenchymal Stem Cells into Tendon Progenitor Cells by Ectopic Expression of ScleraxisSemantic proximity Read ↗

Stepwise Differentiation of Human Embryonic Stem Cells Promotes Tendon Regeneration by Secreting Fetal Tendon Matrix and Differentiation FactorsSemantic proximity Read ↗

Molecular dissection of tendon development and healing: Insights into tenogenic phenotypes and functions.Semantic proximity Read ↗

Emerging ideas: Evaluation of stem cells genetically modified with scleraxis to improve rotator cuff healing.Semantic proximity Read ↗

Transient Scleraxis Overexpression Combined with Cyclic Strain Enhances Ligament Cell DifferentiationSemantic proximity Read ↗

Mechanical force modulates scleraxis expression in bioartificial tendons.Semantic proximity Read ↗

Embryonic mechanical and soluble cues regulate tendon progenitor cell gene expression as a function of developmental stage and anatomical origin.Semantic proximity Read ↗

Novel roles for scleraxis in regulating adult tenocyte functionSemantic proximity Read ↗

Regulation of tendon differentiation by scleraxis distinguishes force-transmitting tendons from muscle-anchoring tendons.Semantic proximity Read ↗

⌁Select a neighboring publication to make it the new centre.