Article
Cell polarity in Saccharomyces cerevisiae depends on proper localization of the Bud9 landmark protein by the EKC/KEOPS complex.
Genetics - 1 Aug 2011
Kato Yu, Kawasaki Hiroshi, Ohyama Yoshifumi, Morishita Takashi, Iwasaki Hiroshi, Kokubo Tetsuro, Hirano Hisashi
Abstract excerpt
In diploid Saccharomyces cerevisiae cells, bud-site selection is determined by two cortical landmarks, Bud8p and Bud9p, at the distal and proximal poles, respectively. Their localizations depend on the multigenerational proteins Rax1p/Rax2p. Many genes involved in bud-site selection were identified previously by genome-wide screening of deletion mutants, which identified BUD32 that causes a random budding in...
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