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Article

BUD2 encodes a GTPase-activating protein for Bud1/Rsr1 necessary for proper bud-site selection in yeast.

Nature - 16 Sept 1993

Park H O, Chant J, Herskowitz I

Abstract excerpt

Cells of the budding yeast Saccharomyces cerevisiae bud at either axial or bipolar sites depending on their cell type. Bud-site selection directs both cell polarity and the cytoskeletal orientation during budding and is determined by at least five genes: BUD1/RSR1, BUD2, BUD3, BUD4 and BUD5. Mutants defective in BUD1, BUD2 or BUD5 choose bud sites randomly. Bud1 protein (Bud1p) has sequence similarity to Ras, a...

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Identifiers

PMID: 8371782
DOI: 10.1038/365269a0

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

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Related research

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Research trail→

Click a neighbor to travelStep 1 · 12 closest

BUD2 encodes a GTPase-activating protein for Bud1/Rsr1 necessary for proper bud-site selection in yeast.PMID 8371782Read ↗

Yeast BUD5, encoding a putative GDP-GTP exchange factor, is necessary for bud site selection and interacts with bud formation gene BEM1.Semantic proximity Read ↗

Specific residues of the GDP/GTP exchange factor Bud5p are involved in establishment of the cell type-specific budding pattern in yeast.Semantic proximity Read ↗

Localization of Bud2p, a GTPase-activating protein necessary for programming cell polarity in yeast to the presumptive bud site.Semantic proximity Read ↗

A mechanism of Bud1p GTPase action suggested by mutational analysis and immunolocalization.Semantic proximity Read ↗

Two active states of the Ras-related Bud1/Rsr1 protein bind to different effectors to determine yeast cell polarity.Semantic proximity Read ↗

A GDP/GTP exchange factor involved in linking a spatial landmark to cell polarity.Semantic proximity Read ↗

Genetic control of bud site selection in yeast by a set of gene products that constitute a morphogenetic pathway.Semantic proximity Read ↗

Localization of the Rsr1/Bud1 GTPase involved in selection of a proper growth site in yeast.Semantic proximity Read ↗

Interactions among Rax1p, Rax2p, Bud8p, and Bud9p in marking cortical sites for bipolar bud-site selection in yeast.Semantic proximity Read ↗

The BUD4 protein of yeast, required for axial budding, is localized to the mother/BUD neck in a cell cycle-dependent manner.Semantic proximity Read ↗

Asymmetrically localized Bud8p and Bud9p proteins control yeast cell polarity and development.Semantic proximity Read ↗

The Rsr1/Bud1 GTPase interacts with itself and the Cdc42 GTPase during bud-site selection and polarity establishment in budding yeast.Semantic proximity Read ↗

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