Article
Differential contribution of Bud6p and Kar9p to microtubule capture and spindle orientation in S. cerevisiae.
The Journal of cell biology - 25 Oct 2004
Huisman Stephen M, Bales Olivia A M, Bertrand Marie, Smeets Monique F M A, Reed Steven I, Segal Marisa
Abstract excerpt
In Saccharomyces cerevisiae, spindle orientation is controlled by a temporal and spatial program of microtubule (MT)-cortex interactions. This program requires Bud6p/Aip3p to direct the old pole to the bud and confine the new pole to the mother cell. Bud6p function has been linked to Kar9p, a protein guiding MTs along actin cables. Here, we show that Kar9p does not mediate Bud6p functions in spindle orientation....
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