Article
Subcellular localization of Axl1, the cell type-specific regulator of polarity.
Current biology : CB - 6 Aug 2002
Lord Matthew, Inose Fumika, Hiroko Takatoshi, Hata Toshihiro, Fujita Atsushi, Chant John
Abstract excerpt
Bud-site selection in yeast offers an attractive system for studying cell polarity and asymmetric division. Haploids divide in an axial pattern, whereas diploids divide in a bipolar pattern. AXL1 is expressed in haploids but not diploids, and ectopic expression of AXL1 in diploids converts their bipolar budding pattern to an axial pattern. How Axl1 acts as a switch between the bipolar and axial patterns is not...
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