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Article

Localization of Bud2p, a GTPase-activating protein necessary for programming cell polarity in yeast to the presumptive bud site.

Genes & development - 1 Aug 1999

Park H O, Sanson A, Herskowitz I

Abstract excerpt

Yeast cells of different cell type exhibit distinct budding patterns that reflect the organization of the actin cytoskeleton. Bud1p (Rsr1p), a Ras-like GTPase, and Bud2p, a GTPase-activating protein for Bud1p, are essential for proper budding pattern. We show that Bud2p is localized at the presumptive bud site in G(1) cells in all cell types and that this localization is independent of Bud1p. Bud2p subsequently...

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Source

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Identifiers

PMID: 10444589
DOI: 10.1101/gad.13.15.1912
PMCID: PMC316924

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

Related research

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Research trail→

Click a neighbor to travelStep 1 · 12 closest

Localization of Bud2p, a GTPase-activating protein necessary for programming cell polarity in yeast to the presumptive bud site.PMID 10444589Read ↗

BUD2 encodes a GTPase-activating protein for Bud1/Rsr1 necessary for proper bud-site selection in yeast.Semantic proximity Read ↗

A GDP/GTP exchange factor involved in linking a spatial landmark to cell polarity.Semantic proximity Read ↗

Specific residues of the GDP/GTP exchange factor Bud5p are involved in establishment of the cell type-specific budding pattern in yeast.Semantic proximity Read ↗

Two active states of the Ras-related Bud1/Rsr1 protein bind to different effectors to determine yeast cell polarity.Semantic proximity Read ↗

A mechanism of Bud1p GTPase action suggested by mutational analysis and immunolocalization.Semantic proximity Read ↗

Yeast BUD5, encoding a putative GDP-GTP exchange factor, is necessary for bud site selection and interacts with bud formation gene BEM1.Semantic proximity Read ↗

Localization of the Rsr1/Bud1 GTPase involved in selection of a proper growth site in yeast.Semantic proximity Read ↗

Interactions among Rax1p, Rax2p, Bud8p, and Bud9p in marking cortical sites for bipolar bud-site selection in yeast.Semantic proximity Read ↗

The Rsr1/Bud1 GTPase interacts with itself and the Cdc42 GTPase during bud-site selection and polarity establishment in budding yeast.Semantic proximity Read ↗

Asymmetrically localized Bud8p and Bud9p proteins control yeast cell polarity and development.Semantic proximity Read ↗

The BUD4 protein of yeast, required for axial budding, is localized to the mother/BUD neck in a cell cycle-dependent manner.Semantic proximity Read ↗

A novel role for the GTPase-activating protein Bud2 in the spindle position checkpoint.Semantic proximity Read ↗

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