Article
Rax1, a protein required for the establishment of the bipolar budding pattern in yeast.
Gene - 3 Mar 2004
Fujita Atsushi, Lord Matthew, Hiroko Takatoshi, Hiroko Fumika, Chen Tracy, Oka Chitoshi, Misumi Yoshio, Chant John
Abstract excerpt
In Saccharomyces cerevisiae, cell type determines two distinct spatial budding patterns. Haploid cells exhibit an axial pattern, whereas diploid cells exhibit a bipolar pattern. Axl1, a member of the insulin-degrading enzyme (IDE) family, is the key morphological determinant for the haploid axial pattern. Here we identified a novel gene, RAX1, specifically required for the bipolar budding pattern. Loss of RAX1...
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