Article
Polarized growth controls cell shape and bipolar bud site selection in Saccharomyces cerevisiae.
Molecular and cellular biology - 1 Jul 2000
Sheu Y J, Barral Y, Snyder M
Abstract excerpt
We examined the relationship between polarized growth and division site selection, two fundamental processes important for proper development of eukaryotes. Diploid Saccharomyces cerevisiae cells exhibit an ellipsoidal shape and a specific division pattern (a bipolar budding pattern). We found that the polarity genes SPA2, PEA2, BUD6, and BNI1 participate in a crucial step of bud morphogenesis, apical growth....
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