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[Analyzing the mutations of rpoB gene in Mycobacterium tuberculosis clinical isolates by probe melting analysis assay].

Zhonghua yu fang yi xue za zhi [Chinese journal of preventive medicine] - 1 Mar 2011

Niu Jian-jun, Zhang Yi, Wen Hui-xin, Liu Xin, Hu Si-yu, Li Qing-ge

Abstract excerpt

OBJECTIVE: To evaluate the clinical performance of a probe melting analysis (PMA)-based real-time PCR detection kit in rapid detection of rifampin-resistant mutations in Mycobacterium tuberculosis (MTB). METHODS: The specificity of the assay was evaluated by detecting 37 non-tuberculous mycobacteria (NTM), and the detection limit of the method was evaluated by genomic DNA of a standard strain H37Rv. Finally, 962...

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Identifiers

PMID: 21624233

Genes

NTM

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 5 Sept 2026. Manifest publication-graph-cohort-2026-09-05.1.

Source receipt: pubmed, retrieved 5 Sept 2026.

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