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Article

Prognostic significance of FOXL2 mutation and mRNA expression in adult and juvenile granulosa cell tumors of the ovary.

Modern pathology : an official journal of the United States and Canadian Academy of Pathology, Inc - 1 Oct 2011

D'Angelo Emanuela, Mozos Ana, Nakayama Daiei, Espinosa Iñigo, Catasus Lluis, Muñoz Josefina, Prat Jaime

Abstract excerpt

Recently, mutation of the FOXL2 gene has been consistently identified in adult granulosa cell tumors of the ovary. The purpose of this study is to investigate whether the FOXL2 mutation and mRNA expression have a role in the pathogenesis of juvenile and adult granulosa cell tumors and influence tumor progression. Thirty-four adult granulosa cell tumors and 20 juvenile granulosa cell tumors were examined for the...

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Identifiers

PMID: 21623383
DOI: 10.1038/modpathol.2011.95

Genes

FOXL2

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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Prognostic significance of FOXL2 mutation and mRNA expression in adult and juvenile granulosa cell tumors of the ovary.PMID 21623383Read ↗

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Mutational Analysis (c.402C>G) of the FOXL2 Gene and Immunohistochemical Expression of the FOXL2 Protein in Testicular Adult Type Granulosa Cell Tumors and Incompletely Differentiated Sex Cord Stromal TumorsSemantic proximity Read ↗

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Identification and Validation of Differential Phosphorylation Sites of the Nuclear FOXL2 Protein as Potential Novel Biomarkers for Adult-Type Granulosa Cell Tumors.Semantic proximity Read ↗

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