Discover Community Create You

Loading publication...

Noodle always counts identifier-free feature events for service operation. With your permission, Google Analytics can also estimate audience and engagement. Search text, publication identifiers, cookies, IP addresses and browser fingerprints are never included in Noodle's first-party event counters.

Privacy details

Article

Latent TGF-β binding protein 3 identifies a second heart field in zebrafish.

Nature - 29 May 2011

Zhou Yong, Cashman Timothy J, Nevis Kathleen R, Obregon Pablo, Carney Sara A, Liu Yan, Gu Aihua, Mosimann Christian, Sondalle Samuel, Peterson Richard E, Heideman Warren, Burns Caroline E, Burns C Geoffrey

Abstract excerpt

The four-chambered mammalian heart develops from two fields of cardiac progenitor cells distinguished by their spatiotemporal patterns of differentiation and contributions to the definitive heart. The first heart field differentiates earlier in lateral plate mesoderm, generates the linear heart tube and ultimately gives rise to the left ventricle. The second heart field (SHF) differentiates later in pharyngeal...

Read the complete abstract on PubMed

Topics

Share this publication in a Topic to start or enrich a Post.

Share to Cardiovascular Abnormalities
Share to Cell Lineage

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Share to Gene Knockdown Techniques

Share to Homeobox Protein Nkx-2.5

Share to Latent TGF-beta Binding Proteins

Share to Myocardium

Share to Zebrafish Proteins

Source

Open in PubMed Open full text

Identifiers

PMID: 21623370
DOI: 10.1038/nature10094
PMCID: PMC3319150

Genes

SHF

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

Related research

Semantic proximity does not establish scientific evidence.

Research trail→

Click a neighbor to travelStep 1 · 12 closest

Latent TGF-β binding protein 3 identifies a second heart field in zebrafish.PMID 21623370Read ↗

Zebrafish second heart field development relies on progenitor specification in anterior lateral plate mesoderm and <i>nkx2.5</i> functionSemantic proximity Read ↗

Tbx2 and Tbx3 Regulate the Dynamics of Cell Proliferation during Heart RemodelingSemantic proximity Read ↗

Unique developmental trajectories and genetic regulation of ventricular and outflow tract progenitors in the zebrafish second heart fieldSemantic proximity Read ↗

A fate map of Tbx1 expressing cells reveals heterogeneity in the second cardiac fieldSemantic proximity Read ↗

Continuous addition of progenitors forms the cardiac ventricle in zebrafishSemantic proximity Read ↗

Pbx4 limits heart size and fosters arch artery formation by partitioning second heart field progenitors and restricting proliferationSemantic proximity Read ↗

Embryonic Tbx3+ cardiomyocytes form the mature cardiac conduction system by progressive fate restrictionSemantic proximity Read ↗

FGF signaling enforces cardiac chamber identity in the developing ventricleSemantic proximity Read ↗

Prrx1b restricts fibrosis and promotes Nrg1-dependent cardiomyocyte proliferation during zebrafish heart regenerationSemantic proximity Read ↗

Development of the human heartSemantic proximity Read ↗

Ventricular, atrial and outflow tract heart progenitors arise from spatially and molecularly distinct regions of the primitive streakSemantic proximity Read ↗

Zebrafish in the Study of Early Cardiac DevelopmentSemantic proximity Read ↗

⌁Select a neighboring publication to make it the new centre.