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Zebrafish in the Study of Early Cardiac Development

15 Mar 2012

Abstract excerpt

Heart development is a complex process that involves cell specification and differentiation, as well as elaborate tissue morphogenesis and remodeling, to generate a functional organ. The zebrafish has emerged as a powerful model system to unravel the basic genetic, molecular, and cellular mechanisms of cardiac development and function. We summarize and discuss recent discoveries on early cardiac specification and...

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PMID: 22427324
DOI: 10.1161/circresaha.111.246504

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