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Article

Interactions between UvrA and UvrB: the role of UvrB's domain 2 in nucleotide excision repair.

The EMBO journal - 7 Jul 2004

Truglio James J, Croteau Deborah L, Skorvaga Milan, DellaVecchia Matthew J, Theis Karsten, Mandavilli Bhaskar S, Van Houten Bennett, Kisker Caroline

Abstract excerpt

Nucleotide excision repair (NER) is a highly conserved DNA repair mechanism present in all kingdoms of life. UvrB is a central component of the bacterial NER system, participating in damage recognition, strand excision and repair synthesis. None of the three presently available crystal structures of UvrB has defined the structure of domain 2, which is critical for the interaction with UvrA. We have solved the...

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Identifiers

PMID: 15192705
DOI: 10.1038/sj.emboj.7600263
PMCID: PMC449773

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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