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Effects of BRAF V600E and NRAS mutational status on the progression‑free survival and clinicopathological characteristics of patients with melanoma

24 Nov 2022

Abstract excerpt

Hotspot mutations of the BRAF and NRAS genes are the most common genetic alterations in invasive cutaneous melanoma; however, the prognostic significance of BRAF and NRAS co‑mutations remains controversial. The present study aimed to determine the association between NRAS and BRAF mutation status and the clinicopathological characteristics of patients with stage IA‑IIC melanoma. A total of 118 patients who...

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Identifiers

PMID: 36478905
DOI: 10.3892/ol.2022.13613

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