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Article

NRAS and BRAF mutations in melanoma tumours in relation to clinical characteristics: a study based on mutation screening by pyrosequencing.

Melanoma research - 1 Dec 2006

Edlundh-Rose Esther, Egyházi Suzanne, Omholt Katarina, Månsson-Brahme Eva, Platz Anton, Hansson Johan, Lundeberg Joakim

Abstract excerpt

We have previously demonstrated the use of pyrosequencing to investigate NRAS [neuroblastoma RAS viral (v-ras) oncogene homolog] mutations in melanoma biopsies. Here, we expanded the analysis to include BRAF (V-raf murine sarcoma viral oncogene homolog B1), another member of the Ras-Raf-mitogen-activated protein kinase (MAPK) signalling pathway, and analysed a total of 294 melanoma tumours from 219 patients....

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Source

Identifiers

PMID: 17119447
DOI: 10.1097/01.cmr.0000232300.22032.86

Genes

BRAF
NRAS

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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