Article
Increased risk for distant metastasis in patients with familial early-stage breast cancer and high EZH2 expression.
Breast cancer research and treatment - 1 Apr 2012
Alford Sharon Hensley, Toy Katherine, Merajver Sofia D, Kleer Celina G
Abstract excerpt
The identification of women with early-stage breast cancer who will develop distant metastasis may improve clinical management. The transcriptional regulator Enhancer of Zeste-2 (EZH2) is overexpressed in invasive breast carcinoma compared with benign breast tissues, with maximal expression in breast cancer metastasis. In this article, our purpose was to investigate the performance of EZH2 protein detection as a...
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