Article
Correlations of EZH2 and SMYD3 gene polymorphisms with breast cancer susceptibility and prognosis.
Bioscience reports - 28 Feb 2018
Ma Shao-Jun, Liu Yan-Mei, Zhang Yue-Lang, Chen Ming-Wei, Cao Wei
Abstract excerpt
The aim of the present study was to investigate the correlation of enhancer of Zeste homolog 2 (EZH2) and SET and MYND domain containing 3 (SMYD3) gene polymorphisms with breast cancer susceptibility and prognosis. A total of 712 patients with breast cancer and 783 healthy individuals were selected. Normal breast epithelial cells MCF-10A and breast cancer cells MCF-7, MDA-MB-231, T47D, and Bcap-37 were cultured....
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