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Article

EZH2 knockdown suppresses the growth and invasion of human inflammatory breast cancer cells

27 Sept 2013

Abstract excerpt

INTRODUCTION: Inflammatory breast cancer (IBC) is the most metastatic variant of breast cancer with the poorest survival in all types of breast cancer patients and presently therapeutic targets for IBC are very limited. Enhancer of zeste homolog 2 (EZH2) is frequently expressed in human IBC and its expression positively correlates with worse clinical outcome. However, the molecular basis for EZH2 promoting IBC...

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PMID: 24294976
DOI: 10.1186/1756-9966-32-70

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