Article
KIR2DS3 is associated with protection against acute myeloid leukemia.
Iranian journal of immunology : IJI - 1 Mar 2010
Shahsavar Farhad, Tajik Nader, Entezami Kobra-Zinat, Fallah Radjabzadeh Masoomeh, Asadifar Behnam, Alimoghaddam Kamran, Ostadali Dahaghi Mohammadreza, Jalali Arash, Ghashghaie Andisheh, Ghavamzadeh Ardeshir
Abstract excerpt
BACKGROUND: Interaction between killer cell immunoglobulin-like receptors (KIR) and human leukocyte antigen (HLA) class I molecules is important for regulation of natural killer (NK) cell function. OBJECTIVE: The aim of this study was to investigate the impact of compound KIR-HLA genotype on susceptibility to acute leukemia. METHODS: Cohorts of Iranian patients with acute myeloid leukemia (AML; n=40) and acute...
Read the complete abstract on PubMedTopics
Share this publication in a Topic to start or enrich a Post.
