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Article

Association of killer cell immunoglobulin-like receptors and their cognate HLA class I ligands with susceptibility to acute myeloid leukemia in Iranian patients.

Scientific reports - 15 Jul 2023

Mirzazadeh Sara, Bemani Peyman, Halimi Hossein, Sanaee Mohammad Nabi, Karami Narges, Ramzi Mani, Farjadian Shirin

Abstract excerpt

Acute myeloid leukemia (AML) is one of the most prevalent leukemia in adults. Among the various NK receptors, killer immunoglobulin-like receptors (KIRs) carry out indispensable roles in NK cell development and function through engaging with class I human leukocyte antigens (HLA-I) as their ligands. Besides divergent KIR and HLA loci, KIR/HLA-I combinations have a significant effect on NK cell response. In this...

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Identifiers

PMID: 37454198
DOI: 10.1038/s41598-023-38479-x
PMCID: PMC10349836

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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